Tocopheryl Acetate (Vitamin E)
Tocopheryl Acetate is a synthetic, stable form of Vitamin E, which is a key fat-soluble antioxidant. It plays a vital role in protecting cellular membranes from oxidative damage, supporting immune health, and maintaining healthy skin and eyes. In pediatric patients, it is primarily used to treat deficiency states, particularly those associated with cystic fibrosis, chronic cholestatic hepatobiliary disease, or abetalipoproteinemia.
Dosage by Body Weight
Pediatric dosing of Vitamin E is highly variable depending on whether it is used for daily supplementation or therapeutic treatment of malabsorption. Standard doses are expressed in International Units (IU). Always administer with food or milk to enhance absorption. Consult a pediatrician before administration, as excess fat-soluble vitamins can accumulate in the body.
- Body Weight
- Below 5 kg
- Dose
- 3 to 5 IU daily (supplemental) or 25 IU daily (therapeutic)
- Frequency
- Once daily
- Tracking Notes
- Use strictly under medical supervision, especially in premature infants, to avoid toxicity and adverse gut effects.
- Body Weight
- 5-7 kg
- Dose
- 5 to 8 IU daily (supplemental) or 25 to 50 IU daily (therapeutic)
- Frequency
- Once daily
- Tracking Notes
- Administer liquid drops directly or mix with milk/formula. Do not exceed the prescribed dose.
- Body Weight
- 8-10 kg
- Dose
- 6 to 10 IU daily (supplemental) or 50 to 100 IU daily (therapeutic)
- Frequency
- Once daily
- Tracking Notes
- Doses should be adjusted based on serum alpha-tocopherol levels if treating chronic malabsorption.
- Body Weight
- 11-15 kg
- Dose
- 9 to 15 IU daily (supplemental) or 100 to 150 IU daily (therapeutic)
- Frequency
- Once daily
- Tracking Notes
- The tolerable upper intake level (UL) for children aged 1-3 years is 300 IU (200 mg) per day.
- Body Weight
- 16-20 kg
- Dose
- 11 to 20 IU daily (supplemental) or 100 to 200 IU daily (therapeutic)
- Frequency
- Once daily
- Tracking Notes
- Ensure adequate dietary fat intake to facilitate absorption. Tolerable upper intake limit is 450 IU daily for ages 4-8.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | 3 to 5 IU daily (supplemental) or 25 IU daily (therapeutic) | Once daily | Use strictly under medical supervision, especially in premature infants, to avoid toxicity and adverse gut effects. |
| 5-7 kg | 5 to 8 IU daily (supplemental) or 25 to 50 IU daily (therapeutic) | Once daily | Administer liquid drops directly or mix with milk/formula. Do not exceed the prescribed dose. |
| 8-10 kg | 6 to 10 IU daily (supplemental) or 50 to 100 IU daily (therapeutic) | Once daily | Doses should be adjusted based on serum alpha-tocopherol levels if treating chronic malabsorption. |
| 11-15 kg | 9 to 15 IU daily (supplemental) or 100 to 150 IU daily (therapeutic) | Once daily | The tolerable upper intake level (UL) for children aged 1-3 years is 300 IU (200 mg) per day. |
| 16-20 kg | 11 to 20 IU daily (supplemental) or 100 to 200 IU daily (therapeutic) | Once daily | Ensure adequate dietary fat intake to facilitate absorption. Tolerable upper intake limit is 450 IU daily for ages 4-8. |
Formulation
Purpose
Prevention and treatment of Vitamin E deficiency, antioxidant support, and nutritional supplementation in malabsorption syndromes.
Generic Name
Tocopheryl Acetate (Vitamin E)Branded Drug Names
Tocopheryl Acetate (Vitamin E) is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.